|
KMID : 0931320140140030187
|
|
대한상부위장관.헬리코박터학회지
2014 Volume.14 No. 3 p.187 ~ p.193
|
|
|
Clinical Outcomes of the Endoscopic Treatments for the Early Esophageal Carcinoma and Dysplasia
|
|
Kim Cheol
Hong Su-Jin
Han Jae-Pil
Jung Hee-Jae
Jeong Eun-Soo
Goong Hyeon-Jeong
Kim Hee-Jun
Lee Seoung-Ho
Ko Bong-Min
Lee Moon Sung
|
|
|
Abstract
|
|
|
Background/Aims: Esophageal cancer and dysplasia are relatively rare in Korea, compared to other Far Eastern countries. So, the feasibility and safety of endoscopic treatments for these diseases is not well established in Korea. This study aimed to assess the technical feasibility, safety and the clinical outcomes of endoscopic treatment for esophageal epithelial lesions.
Materials and Methods: Between April 2005 and March 2013, 25 esophageal epithelial lesions from 22 patients were treated with endoscopic treatment such as endoscopic submucosal dissection or endoscopic mucosal resection.
Results: Of the 25 lesions, 11 lesions were treated with endoscopic submucosal dissection (ESD) (ESD group) and 14 lesions with endoscopic mucosal resection (EMR group). In the ESD group, the diagnosis was squamous cell carcinoma in 7 patients (64%), high grade dysplasia in 3 patients (27%), and low grade dysplasia in 1 patient (9%). In the EMR group, thediagnosis was squamous cell carcinoma in 8 patients (57%), high grade dysplasia in 2 patients (14%), and low grade dysplasia in 4 patients (29%). En blocresection rates were 100% in ESD and 42.9% in EMR, respectively. For the median 12 months follow up period, there was no re-currence in the ESD group. However, there were three recurrences in the EMR group.
Conclusions: Endoscopic treatment for esophageal epithelial lesions is safe and feasible therapeutic modalities. Especially, ESD can provide higher rate of en bloc and curative resection for early esophageal cancer and dysplasia.
|
|
|
KEYWORD
|
|
|
Early esophageal cancer, Esophageal dysplasia, Endoscopic submucosal dissection, Endoscopic mucosal resection
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|